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22252-07-9

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22252-07-9 Structure

22252-07-9 Structure
IdentificationBack Directory
[Name]

1-LINOLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHORYLCHOLINE
[CAS]

22252-07-9
[Synonyms]

Lysophosphatidylcholine 18:2
1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC
1-LINOLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHORYLCHOLINE
[Molecular Formula]

C26H50NO7P
[MDL Number]

MFCD02259125
[MOL File]

22252-07-9.mol
[Molecular Weight]

519.66
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

PBS (pH 7.2): 2 mg/ml
[form ]

Oil
[color ]

White to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS06,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H310-H331-H315-H319-H351-H361-H372
[Precautionary statements ]

P201-P202-P260-P262-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P308+P313-P321-P314-P330-P361+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard InformationBack Directory
[Definition]

ChEBI: 1-linoleoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 18:2 in which the acyl group at position 1 is (9Z,12Z)-octadecadienoyl. It has a role as a mouse metabolite. It is a lysophosphatidylcholine(18:2/0:0) and a linoleoyl-sn-glycero-3-phosphocholine. It is functionally related to a linoleic acid.
[Biological Activity]

1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid at the sn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1 Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.2
[References]

1.Okudaira, M., Inoue, A., Shuto, A., et al.Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MSJ. Lipid Res.55(10)2178-2192(2014) 2.Gall, W.E., Beebe, K., Lawton, K.A., et al.α-Hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic populationPLoS One5(5)e10883(2010)
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