ChemicalBook--->CAS DataBase List--->2229042-77-5

2229042-77-5

2229042-77-5 Structure

2229042-77-5 Structure
IdentificationBack Directory
[Name]

ZL0454
[CAS]

2229042-77-5
[Synonyms]

ZL0454
[Molecular Formula]

C18H22N4O3S
[MDL Number]

MFCD31813659
[MOL File]

2229042-77-5.mol
[Molecular Weight]

374.46
Chemical PropertiesBack Directory
[Boiling point ]

630.6±65.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 50 mg/mL (133.53 mM; Need ultrasonic)
[form ]

Solid
[pka]

9.30±0.36(Predicted)
[color ]

Brown to reddish brown
Hazard InformationBack Directory
[Biological Activity]

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.
[References]

[1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.
2229042-77-5 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Website: www.bio-fount.com
Company Name: cjbscvictory  
Tel: 13348960310 13348960310
Website: http://www.weikeqi-biotech.com/
Company Name: InvivoChem  
Tel: 13549236410
Website: https://www.invivochem.cn/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Website: www.ruidiresearch.com
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Website: http://www.synzest.com
Tags:2229042-77-5 Related Product Information
49671-76-3 1181226-02-7 2229039-45-4