ChemicalBook--->CAS DataBase List--->2230821-40-4

2230821-40-4

2230821-40-4 Structure

2230821-40-4 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2230821-40-4
[Synonyms]

SJF 1521
[Molecular Formula]

C57H61ClFN7O9S
[MOL File]

2230821-40-4.mol
[Molecular Weight]

1074.66
Chemical PropertiesBack Directory
[Boiling point ]

1160.1±65.0 °C(Predicted)
[density ]

1.314±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO|107.47|100|
[pka]

13.54±0.46(Predicted)
Safety DataBack Directory
[HS Code ]

2934100090
Hazard InformationBack Directory
[Description]

SJF 1521 is a selective EGFR PROTAC?? Degrader based on the EGFR inhibitor lapatinib linked to a von Hippel-Lindau (VHL) recruiting ligand by PEG3. SJF 1521 exhibits selectivity for EGFR, including mutant forms, over HER2 and induces degradation of EGFR in OVCAR8 cells.
[storage]

Store at -20°C
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