| Identification | Back Directory | [Name]
JI-130) | [CAS]
2234271-86-2 | [Synonyms]
JI-130)
JI130
(JI 130
2-Propenamide, 3-(7-methoxy-1H-indol-3-yl)-N-[2-[2-(2-propen-1-yloxy)phenyl]ethyl]-, (2E)- | [Molecular Formula]
C23H24N2O3 | [MOL File]
2234271-86-2.mol | [Molecular Weight]
376.45 |
| Hazard Information | Back Directory | [Description]
JI130 is an inhibitor of the cancer-associated transcription factor Hes1 via the PHB2 chaperone. JI130 stabilizes PHB2's interaction with Hes1 outside the nucleus, inducing G2/M cell cycle arrest. |
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