| Identification | Back Directory | [Name]
α-Ethyltryptamine | [CAS]
2235-90-7 | [Synonyms]
Nsc88061
Ro 3-1932
Etryptamine
AURORA KA-7710
α-Ethyltryptamine
α-Ethyltryptamine
3-Indolylbutylamine
ALPHA-ETHYLTRYPTAMINE
A-ETHYLTRYPTAMINE HCL
3-(2-AMINOBUTYL)INDOLE
Indole, 3-(2-aminobutyl)-
3-(2-Aminobutyl)-1H-indole
α-Ethyltryptamine USP/EP/BP
1-(1H-indol-3-yl)butan-2-amine
1H-Indole-3-ethanamine, α-ethyl-
α-Ethyl-1H-indole-3-ethan-1-amine
1-(1H-INDOL-3-YLMETHYL)-PROPYLAMINE
1H-Indole-3-ethanamine, .alpha.-ethyl-
α-Ethyltryptamine (exempt preparation)
.alpha.-Ethyltryptamine (exempt preparation) | [Molecular Formula]
C12H16N2 | [MDL Number]
MFCD00047192 | [MOL File]
2235-90-7.mol | [Molecular Weight]
188.27 |
| Chemical Properties | Back Directory | [Melting point ]
97-99° | [Boiling point ]
313.29°C (rough estimate) | [density ]
0.9520 (rough estimate) | [refractive index ]
1.5600 (estimate) | [solubility ]
DMF: 11 mg/ml; DMSO: 5 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml | [form ]
A crystalline solid | [pka]
17.22±0.30(Predicted) | [Water Solubility ]
0.51g/L(room temperature) |
| Hazard Information | Back Directory | [Originator]
Monase,Upjohn,US,1961 | [Uses]
α-Ethyltryptamine (E931900) is used as a stimulant and entactogen that have actions at multiple central nervous system (CNS) receptor sites.
| [Definition]
ChEBI: Etryptamine is a member of indoles. | [Manufacturing Process]
A mixture of 5 parts of 3-(2'-ethyl-2'-nitrovinyl)indole in 80 parts of ethanol
saturated with ammonia gas is shaken in an atmosphere of hydrogen at 100
atmospheres pressure and at 20°C in the presence of 1 part of a 5%
palladium on carbon catalyst until the theoretical amount of hydrogen is
absorbed. The catalyst is removed by filtration. The ethanol and ammonia are
then removed from the filtrate by distillation under reduced pressure. The
residual oil is dissolved in 170 parts of dry ether, 50 parts of potassium
hydroxide pellets are added and the solution is kept at 18°C to 22°C for 2
hours. The mixture is filtered and hydrogen chloride is passed into the filtrate
to precipitate crude (α-ethyltryptamine hydrochloride. This is purified by
crystallization from methanol/ethyl acetate and it then has a MP of 221°C. | [Therapeutic Function]
Central stimulant |
|