| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2241644-09-5 | [Synonyms]
DBCO-PEG4-VA-SG3132 | [Molecular Formula]
C80H87N9O16 | [Molecular Weight]
1430.6 |
| Hazard Information | Back Directory | [Biological Activity]
DBCO-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. | [References]
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |
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