| Identification | Back Directory | [Name]
Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- | [CAS]
2242582-40-5 | [Synonyms]
USP30 inhibitor 18
Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- | [Molecular Formula]
C26H28FN3O4S | [MOL File]
2242582-40-5.mol | [Molecular Weight]
497.59 |
| Hazard Information | Back Directory | [Biological Activity]
USP30 inhibitor 18 is a selective USP30 inhibitor with an IC50 of 0.02 μM. USP30 inhibitor 18 increases protein ubiquitination and accelerates mitophagy[1]. | [References]
[1]. Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659. |
|
|