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2244716-55-8

2244716-55-8 Structure

2244716-55-8 Structure
IdentificationBack Directory
[Name]

Octanoic acid, 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl][3-[[2-(methylamino)-3,4-dioxo-1-cyclobuten-1-yl]amino]propyl]amino]-, 1-octylnonyl ester
[CAS]

2244716-55-8
[Synonyms]

heptadecan-9-yl 8-((3-((2-(methylamino)-3,4-dioxocyclobut-1-en-1-yl)amino)propyl)(8-oxo-8-(undecan-3-yloxy)octyl)amino)octanoate
Octanoic acid, 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl][3-[[2-(methylamino)-3,4-dioxo-1-cyclobuten-1-yl]amino]propyl]amino]-, 1-octylnonyl ester
[Molecular Formula]

C52H97N3O6
[MOL File]

2244716-55-8.mol
[Molecular Weight]

860.34
Chemical PropertiesBack Directory
[Boiling point ]

823.8±75.0 °C(Predicted)
[density ]

0.99±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Ethanol: 25 mg/ml
[form ]

Oil
[pka]

9.49±0.50(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H350
[Precautionary statements ]

P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
Hazard InformationBack Directory
[Biological Activity]

Lipid 29 is an ionizable amino lipid (pKa = 6.91) that has been used in combination with other lipids in the formation of lipid nanoparticles.1 Administration of human erythropoietin (EPO) mRNA in lipid 29-containing lipid nanoparticles increases serum EPO levels in mice.
[References]

1.Cornebise, M., Narayanan, E., Xia, Y., et al.Discovery of a novel amino lipid that improves lipid nanoparticle performance through specific interactions with mRNAAdv. Funct. Mater.32(8)2106727(2106721-2106712)(2021)
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