| Identification | Back Directory | [Name]
nAChR agonist CMPI hydrochloride | [CAS]
2250025-94-4 | [Synonyms]
nAChR agonist CMPI hydrochloride | [Molecular Formula]
C18H20Cl2N4O | [MDL Number]
MFCD30742937 | [MOL File]
2250025-94-4.mol | [Molecular Weight]
379.29 |
| Hazard Information | Back Directory | [Biological Activity]
CMPI hydrochloride is a potent positive allosteric modulator of α4β2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for hα4β2 over hα3β2, hα3β4 and hα7. Inhibits (α4)2(β2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 μM, respectively), but not (α4)3(β2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains. | [storage]
Store at -20°C |
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