| Chemical Properties | Back Directory | [Boiling point ]
604.7±50.0 °C(Predicted) | [density ]
1.154±0.06 g/cm3(Predicted) | [form ]
Oil | [pka]
3.39±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
HO-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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| Company Name: |
PurePEG，LLC
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| Tel: |
1.858.408.4567 |
| Website: |
www.purepeg.com |
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