| Identification | Back Directory | [Name]
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 | [CAS]
2250261-59-5 | [Synonyms]
F092 inhibitor
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 | [Molecular Formula]
C20H17N5O2 | [MOL File]
2250261-59-5.mol | [Molecular Weight]
359.38 |
| Chemical Properties | Back Directory | [Boiling point ]
509.0±48.0 °C(Predicted) | [density ]
1.359±0.06 g/cm3(Predicted) | [solubility ]
DMF: 3 mg/ml; DMSO: 5 mg/ml; Ethanol: partially soluble; PBS (pH 7.2): partially soluble | [form ]
A crystalline solid | [pka]
10.70±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Prostaglandin D synthase (hematopoietic-type) inhibitor F092 is an inhibitor of hematopoietic-type prostaglandin D synthase (H-PGDS; KD = 0.14 nM).1 | [References]
1. Takaya, D., Inaka, K., Omura, A., et al. Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies Bioorg. Med. Chem. 26(16),4726-4734(2018). |
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