| Identification | Back Directory | [Name]
ETANIDAZOLE | [CAS]
22668-01-5 | [Synonyms]
Radinyl
SP-2508
SR-2508
nsc301467
ETANIDAZOLE
Etanidazole (SR-2508)
N-(2-Hydroxyethyl)-1H-imidazole-1-acetamide
n-(2-hydroxyethyl)-2-nitro-imidazole-1-acetamid
n-(2-hydroxyethyl)-2-nitro-1h-imidazole-1-acetamid
N-[2-HYDROXYETHYL]-2-NITRO-1H-IMIDAZOLE-1-ACETAMIDE
n-(2-hydroxyethyl)-1-(2-nitro-1-imidazolyl)acetamide
1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro- | [Molecular Formula]
C7H10N4O4 | [MDL Number]
MFCD00156108 | [MOL File]
22668-01-5.mol | [Molecular Weight]
214.18 |
| Chemical Properties | Back Directory | [Melting point ]
162-163° (Beaman); mp 164.5-165° (Lee) | [Boiling point ]
354.3°C (rough estimate) | [density ]
1.4480 (rough estimate) | [refractive index ]
1.6700 (estimate) | [storage temp. ]
2-8°C | [solubility ]
Acetone (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.74±0.46(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Antineoplastic (hypoxic cell radiosensitizer). | [Uses]
Etanidazole is a kind of hypoxic radiosensitizer (a drug that sensitizes tumour cells to radiation therapy). Etanidazole is used in conjunction with Paclitaxel (P132500) to treat glioma, and is also used with Carboplatin (C177500) to treat advanced ovarian cancer. | [Definition]
ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells. | [Brand name]
Radinyl (Roberts Pharmaceutical). |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|