| Identification | Back Directory | [Name]
URAT1 inhibitor 1 | [CAS]
2268720-62-1 | [Synonyms]
URAT1 inhibitor 1
Methanesulfonamide, 1-[[5-bromo-4-[(4-bromo-1-naphthalenyl)methyl]-4H-1,2,4-triazol-3-yl]thio]-N-3-pyridinyl- | [Molecular Formula]
C19H15Br2N5O2S2 | [MDL Number]
MFCD32067902 | [MOL File]
2268720-62-1.mol | [Molecular Weight]
569.29 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (219.57 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1]. | [References]
[1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388. |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
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