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2280037-51-4

2280037-51-4 Structure

2280037-51-4 Structure
IdentificationBack Directory
[Name]

Bobcat339 (Bobcat 339)
[CAS]

2280037-51-4
[Synonyms]

Bobcat399
Bobcat339 (Bobcat 339)
2(1H)-Pyrimidinone, 4-amino-1-[1,1'-biphenyl]-3-yl-5-chloro-
[EINECS(EC#)]

604-604-1
[Molecular Formula]

C16H12ClN3O
[MDL Number]

MFCD32644557
[MOL File]

2280037-51-4.mol
[Molecular Weight]

297.74
Chemical PropertiesBack Directory
[Boiling point ]

489.0±55.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 1 mg/ml,DMSO: 1 mg/ml,DMSO:PBS (pH 7.2) (1:8): 0.11 mg/ml
[form ]

A crystalline solid
[pka]

2.42±0.10(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Biological Activity]

Bobcat339 is a cell penetrantpotent and selective inhibitor of TET1 and TET2 [Ten-eleven translocation methylcytosine dioxygenase (TET) 1 and 2] th at reduces content of 5-hydroxymethyl-cytosine (5hmC) in cultured neurons. Bobcat339 does not inhibit DNMT3a.
[storage]

Store at -20°C
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