| Identification | Back Directory | [Name]
2-Azetidinecarboxamide, 1-[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]-, (2S)- | [CAS]
2286257-25-6 | [Synonyms]
2-Azetidinecarboxamide, 1-[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]-, (2S)- | [Molecular Formula]
C18H19FN2O2 | [MOL File]
2286257-25-6.mol | [Molecular Weight]
314.35 |
| Hazard Information | Back Directory | [Biological Activity]
C3 is an inhibitor of monoamine oxidase B (MAO-B; IC50 = 0.021 μM).1 It is selective for MAO-B over MAO-A (IC50 = 26.8 μM). C3 (0.1, 1, and 3 mg/kg) prevents MPTP-induced decreases in brain dopamine levels in mice. | [storage]
-20°C | [References]
1.Jin, C.-F., Wang, Z.-Z., Chen, K.-Z., et al.Computational fragment-based design facilitates discovery of potent and selective monoamine oxidase-B (MAO-B) inhibitorJ. Med. Chem.63(23)15021-15036(2020)
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