ChemicalBook--->CAS DataBase List--->229018-17-1

229018-17-1

229018-17-1 Structure

229018-17-1 Structure
IdentificationBack Directory
[Name]

2-HydroxyMelatonin
[CAS]

229018-17-1
[Synonyms]

2-HydroxyMelatonin
Melatonin Impurtiy 4
Melatonin 2-Hydroxy Impurity
N-(2-(2-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl)acetamide
Acetamide, N-[2-(2-hydroxy-5-methoxy-1H-indol-3-yl)ethyl]-
[Molecular Formula]

C13H16N2O3
[MDL Number]

MFCD30187118
[MOL File]

229018-17-1.mol
[Molecular Weight]

248.28
Chemical PropertiesBack Directory
[Melting point ]

>124oC (dec.)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Light Yellow to Orange
Hazard InformationBack Directory
[Uses]

2-Hydroxymelatonin, is a metabolite of Melatonin (M215000), which is a hormone found in animals, plants, and microbes. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
[Definition]

ChEBI: 2-hydroxymelatonin is a member of the class of hydroxyindoles that is melatonin in which the hydrogen at position 2 of the indole ring has been replaced by a hydroxy group. A predominant hydroxylated melatonin metabolite in plants. It has a role as a plant metabolite, an antineoplastic agent and an apoptosis inducer. It is a member of acetamides, a member of tryptamines and a member of hydroxyindoles. It is functionally related to a melatonin.
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