| Identification | Back Directory | [Name]
4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- | [CAS]
2311901-93-4 | [Synonyms]
4H-Pyrrolo[3,2-c]pyridin-4-one, 3-[(3-fluoro-2-methoxyphenyl)amino]-1,5,6,7-tetrahydro-2-[3-(2-methoxy-2-methylpropoxy)-4-pyridinyl]- | [Molecular Formula]
C24H27FN4O4 | [MOL File]
2311901-93-4.mol | [Molecular Weight]
454.49 |
| Chemical Properties | Back Directory | [Boiling point ]
663.6±55.0 °C(Predicted) | [density ]
1.275±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
13.39±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
BAY 2476568 is a potent and selective EGFR inhibitor, with IC50s of < 0.2 nM for wild-type EGFR and several mutations (EGFRR ex20insSVD, EGFRR ex20insASV, EGFRR ex20insNPG)[1]. | [References]
[1]. Stephan Siegel, et al. 4h-pyrrolo[3,2-c]pyridin-4-one derivatives. WO2019081486A1. |
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