Identification | Back Directory | [Name]
BOC-LYS(AC)-AMC | [CAS]
233691-67-3 | [Synonyms]
MAL BOC-LYS(AC)-AMC Boc-L-Lys(Ac)-AMC BOC-LYSINE(AC)-AMC HDAC SUBSTRATE (FLUOROMETRIC) (Tert-Butoxy)Carbonyl Lys(Ac)-AMC BOC-LYS(AC)-7-AMINO-4-METHYLCOUMARIN HISTONE DEACETYLASE SUBSTRATE, FLUOROGENIC HISTONE DEACETYLASE SUBSTRATE (FLUOROMETRIC) Nα-Boc-Nε-acetyl-L-lysine 7-amido-4-methylcoumarin Nα-Boc-Nε-acetyl-L-lysine 7-amido-4-methylcoumarin BOC-N-EPSILON-ACETYL-L-LYSINE 7-AMIDO-4-METHYLCOUMARIN N-alpha-Boc-Nepsilon-acetyl-L-lysine 7-amido-4-methylcoumarin N-(4-Methyl-7-coumarinyl)-N-(t-butoxycarbonyl)-N-acetyllysinamide Histone Deacetylase Substrate, Fluorogenic - CAS 233691-67-3 - Calbiochem N-ALPHA-T-BUTOXYCARBONYL-N-EPSILON-ACETYL-L-LYSINE 7-AMIDO-4-METHYLCOUMARIN N-(4-METHYL-7-COUMARINYL)-N-ALPHA-(T-BUTOXYCARBONYL)-N-OMEGA-ACETYLLYSINAMIDE N-(4-METHYL-7-COUMARINYL)-N-ALPHA-(T-BUTOXYCARBONYL)-N-OMEGA-ACETYLLYSINEAMIDE Boc-Lys(Ac)-AMC, MAL, N-(4-Methyl-7-coumarinyl)-N-(t-butoxycarbonyl)-N-acetyllysinamide tert-butyl N-[(1S)-5-acetamido-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]pentyl]carbamate tert-butyl N-[(2S)-6-acetamido-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxohexan-2-yl]carbamate tert-butyl (S)-(6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamate (S)-tert-Butyl (6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamate Carbamic acid, N-[(1S)-5-(acetylamino)-1-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl]pentyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C23H31N3O6 | [MDL Number]
MFCD02683946 | [MOL File]
233691-67-3.mol | [Molecular Weight]
445.51 |
Chemical Properties | Back Directory | [Boiling point ]
732.6±60.0 °C(Predicted) | [density ]
1.209±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml | [form ]
White crystalline solid | [pka]
11.23±0.46(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Description]
Boc-Lys(Ac)-AMC is a fluorescent substrate for histone deacetylases (HDACs). Following deacetylation by an HDAC, Boc-Lys-AMC is cleaved by trypsin and 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify HDAC activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. | [storage]
Store at -20°C |
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