Identification | Back Directory | [Name]
Mal-PEG8-Val-Cit-PAB-MMAE | [CAS]
2353409-69-3 | [Synonyms]
Mal-PEG8-Val-Cit-PAB-MMAE | [Molecular Formula]
C81H131N11O23 | [MDL Number]
MFCD32669864 | [Molecular Weight]
1626.97 |
Chemical Properties | Back Directory | [Boiling point ]
1438.4±65.0 °C(Predicted) | [density ]
1.191±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.29±0.70(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Description]
Mal-PEG8-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains a maleimide PEG8 moiety, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. Mal is reactive with thiol group of antibody. |
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Company Name: |
Abydos Scientific
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Tel: |
025-84767922 18936879710 |
Website: |
http://www.abydoscientific.com/index.html |
Company Name: |
MedChemExpress
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Tel: |
021-58955995 |
Website: |
www.medchemexpress.com |
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