| Identification | Back Directory | [Name]
Benzoic acid, 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]- | [CAS]
2361327-08-2 | [Synonyms]
Benzoic acid, 4-[(1,5-dihydro-5-oxo-2H-[1]benzopyrano[3,4-c]pyridin-3(4H)-yl)carbonyl]- | [Molecular Formula]
C20H15NO5 | [MDL Number]
MFCD34578263 | [MOL File]
2361327-08-2.mol | [Molecular Weight]
349.34 |
| Chemical Properties | Back Directory | [Boiling point ]
652.9±55.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble,Methanol: soluble | [form ]
A crystalline solid | [pka]
3.86±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2; IC50 = 1.6 μM).1 It is selective for MTHFD2 over MTHFD1 (IC50 = >30 μM). | [storage]
Store at -20°C | [References]
1.Kawai, J., Ota, M., Ohki, H., et al.Structure-based design and synthesis of an isozyme-selective MTHFD2 inhibitor with a tricyclic coumarin scaffoldACS Med. Chem. Lett.10(6)893-898(2019)
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DC Chemicals
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