| Identification | Back Directory | [Name]
Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | [CAS]
2361742-30-3 | [Synonyms]
Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | [Molecular Formula]
C16H8ClF3N4O | [MOL File]
2361742-30-3.mol | [Molecular Weight]
364.71 |
| Chemical Properties | Back Directory | [Boiling point ]
496.4±45.0 °C(Predicted) | [density ]
1.51±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
9.65±0.23(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1]. | [storage]
Store at -20°C | [References]
[1]. Ton AT, et al. Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer. Int J Mol Sci. 2022;23(5):2588. Published 2022 Feb 26. |
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