| Identification | Back Directory | [Name]
Benzoic acid, 4-methoxy-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)- | [CAS]
2377643-33-7 | [Synonyms]
3-(2,4-dioxohexahydropyrimidin-1-yl)-4-methoxy-benzoic acid
3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-methoxybenzoic acid
Benzoic acid, 4-methoxy-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)- | [Molecular Formula]
C12H12N2O5 | [MOL File]
2377643-33-7.mol | [Molecular Weight]
264.23 |
| Hazard Information | Back Directory | [Uses]
2-Methoxyphenyl dihydrouracil (Compound 13) is a CRBN ligand, and can be used for synthesis of PROTACs[1]. | [IC 50]
Cereblon | [References]
[1] Wang K, et al. Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor. Bioorg Med Chem Lett. 2024 Jul 15;107:129780. DOI:10.1016/j.bmcl.2024.129780 |
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