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ChemicalBook--->CAS DataBase List--->2381196-79-6

2381196-79-6

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2381196-79-6 Structure

2381196-79-6 Structure
IdentificationBack Directory
[Name]

PEG3-C4-OBn
[CAS]

2381196-79-6
[Synonyms]

PEG3-C4-OBn
[Molecular Formula]

C17H28O4
[MDL Number]

MFCD32689584
[MOL File]

2381196-79-6.mol
[Molecular Weight]

296.4
Chemical PropertiesBack Directory
[Boiling point ]

413.5±35.0 °C(Predicted)
[density ]

1.031±0.06 g/cm3(Predicted)
[solubility ]

Soluble in DMSO
[form ]

Liquid
[pka]

14.37±0.10(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Biological Activity]

PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1. PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].
[References]

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5. [2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.
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