| Identification | Back Directory | [Name]
5beta-Cholan-3alpha,7alpha,24-triol | [CAS]
23848-46-6 | [Synonyms]
CDC-OH
UDC-OH
Reaxys ID: 4472691
Reaxys ID: 2285975
Chenodeoxycholan-24-ol
5β-CHOLAN-3α, 7α, 24-TRIOL
3α,7α,24-Trihydroxy-5β-cholan | [Molecular Formula]
C24H42O3 | [MDL Number]
MFCD00271457 | [MOL File]
23848-46-6.mol | [Molecular Weight]
378.59 |
| Chemical Properties | Back Directory | [Boiling point ]
509.5±25.0 °C(Predicted) | [density ]
1.079±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Dichloromethane; | [form ]
Solid | [pka]
14.79±0.70(Predicted) | [color ]
Off-white Foamy |
| Hazard Information | Back Directory | [Uses]
Chenodeoxycholan-24-ol is an intermediate used in the synthesis of 3α,7α-Dihydroxycoprostanic Acid-d3 (D452517), which is a labelled analogue of 3α,7α-Dihydroxycoprostanic Acid (D452515), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α-Dihydroxycoprostanic Acid. |
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