| Identification | Back Directory | [Name]
1,4,9-Triazaspiro[5.5]undecane, 4-[3-(3,5-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-9-(2-methyl-4-pyridinyl)- | [CAS]
2387510-80-5 | [Synonyms]
1,4,9-Triazaspiro[5.5]undecane, 4-[3-(3,5-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-9-(2-methyl-4-pyridinyl)- | [Molecular Formula]
C25H32N6O3 | [MDL Number]
MFCD32697257 | [MOL File]
2387510-80-5.mol | [Molecular Weight]
464.56 |
| Chemical Properties | Back Directory | [Boiling point ]
654.9±65.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [solubility ]
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl | [form ]
Solid | [pka]
11.65±0.10(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Description]
MRK-740 is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor. It is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4. | [storage]
Store at -20°C |
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