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2434629-02-2

2434629-02-2 Structure

2434629-02-2 Structure
IdentificationBack Directory
[Name]

4-((5-azidopentyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
[CAS]

2434629-02-2
[Synonyms]

4-((5-azidopentyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
[Molecular Formula]

C18H20N6O4
[MOL File]

2434629-02-2.mol
[Molecular Weight]

384.4
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

XUN-29022 is a functionalized cereblon ligand for PROTAC? research and development. It incorporates an E3 ligase ligand plus an alkylC5 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name.
[Uses]

Pomalidomide-C5-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand-Linker conjugate. The azide group can undergo a click chemical reaction[1].
[storage]

Store at -20°C
[References]

[1] Yonghui Sun, et al. Developing potent BTKC481S PROTACs for ibrutinib-resistant malignant lymphoma. Chinese Chemical Letters. Volume 34, Issue 6, June 2023, 107924.
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