| Identification | Back Directory | [Name]
nucleocidin | [CAS]
24751-69-7 | [Synonyms]
T-3018
NSC 521007
nucleocidin
Antibiotic T-3018
LTBCQBSAWAZBDF-XPQPFPQWSA-N
4'-Fluoro-5'-O-sulfamoyladenosine
5'-O-Sulfamoyl-4'-fluoroadenosine
Adenosine, 4'-C-fluoro-, 5'-sulfamate
Sulfamic acid 4'-fluoro-5'-adenosyl ester | [Molecular Formula]
C10H13FN6O6S | [MDL Number]
MFCD01939321 | [MOL File]
24751-69-7.mol | [Molecular Weight]
364.31 |
| Chemical Properties | Back Directory | [Melting point ]
>190° (dec) | [Boiling point ]
747.6±70.0 °C(Predicted) | [density ]
2.23±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
9.15±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Nucleocidin is used in studies relating to novel parasite inhibitors. | [Definition]
ChEBI: Nucleocidin is a nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. It has a role as a bacterial metabolite, an antibacterial agent, a trypanocidal drug, a protein synthesis inhibitor and a nucleoside antibiotic. It is a member of adenosines, an organofluorine compound, a sulfamate ester, a member of 6-aminopurines and a diol. It is functionally related to an adenosine. | [storage]
Store at -20°C |
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