| Identification | Back Directory | [Name]
demethoxycurcumin | [CAS]
24939-17-1 | [Synonyms]
CURCUMINII
demethoxycurcumin b
(E/Z)-Demethoxycurcumin
Desmethoxycurcumin (30 mg)
4-HYDROXYCINNAMOYL(FERULOYL)METHANE
FERULOYL-PARA-HYDROXYCINNAMOYLMETHANE
PARA-HYDROXYCINNAMOYL(FERULOYL)METHANE
1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione | [Molecular Formula]
C20H18O5 | [MOL File]
24939-17-1.mol | [Molecular Weight]
338.35 |
| Chemical Properties | Back Directory | [Boiling point ]
571.4±50.0 °C(Predicted) | [density ]
1.282±0.06 g/cm3(Predicted) | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
8.59±0.46(Predicted) | [color ]
Yellow to orange | [LogP]
3.150 (est) |
| Hazard Information | Back Directory | [Uses]
Desmethoxycurcumin is a derivative of Curcumin (C838500) that regulates anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. It attenuates the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300. | [Definition]
ChEBI: Demethoxycurcumin is a beta-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent. It is a polyphenol, a beta-diketone, an enone and a diarylheptanoid. |
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