| Identification | Back Directory | [Name]
10H,13H-Benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione, 4-amino-9-ethyl-1,2,3,9,12,15-hexahydro-9-hydroxy-, (9S)- | [CAS]
2495742-21-5 | [Synonyms]
(4-NH2)-Exatecan
10H,13H-Benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione, 4-amino-9-ethyl-1,2,3,9,12,15-hexahydro-9-hydroxy-, (9S)- | [Molecular Formula]
C23H21N3O4 | [MOL File]
2495742-21-5.mol | [Molecular Weight]
403.43 |
| Chemical Properties | Back Directory | [Boiling point ]
856.1±65.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture | [form ]
Solid | [pka]
11.23±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
(4-NH2)-Exatecan, a topoisomerase inhibitor derivative extracted from patent US20200306243A1, compound A. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [References]
[1]. Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1. |
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