| Identification | Back Directory | [Name]
2-Propenamide, 3-(3-chlorophenyl)-N-[2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl]-, (2E)- | [CAS]
2505001-54-5 | [Synonyms]
2-Propenamide, 3-(3-chlorophenyl)-N-[2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl]-, (2E)- | [Molecular Formula]
C16H20ClN3O4S | [MOL File]
2505001-54-5.mol | [Molecular Weight]
385.87 |
| Chemical Properties | Back Directory | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 100 mg/mL (259.15 mM; Need ultrasonic) | [form ]
Solid | [pka]
13.21±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells)[1].
SR15006 (1 μM or 10 μM; DLD-1 CRC cells) causes a significant reduction in the levels of tested cyclins over the course of 72 hours[1]. | [References]
[1]. Kim J, et al. The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. Mol Cancer Ther. 2019;18(11):1973-1984. |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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