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25218-38-6

25218-38-6 Structure

25218-38-6 Structure
IdentificationBack Directory
[Name]

3β-OH-7-Oxocholenic Acid
[CAS]

25218-38-6
[Synonyms]

3β-OH-7-Oxocholenic Acid
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Acetonitrile: 1mg/mL; Ethanol: 1mg/mL; Methanol: 1mg/mL
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3
[Definition]

ChEBI: 3beta-Hydroxy-7-oxochol-5-en-24-oic Acid is a bile acid.
[References]

1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat Steroids 15(3),303-326(1970).
2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C J. Lipid Res. 42(10),1571-1577(2001).
3. Maekawa, M., Omura, K., Sekiguchi, S., et al. Identification of two sulfated cholesterol metabolites found in the urine of a patient with Niemann-Pick disease type C as novel candidate diagnostic markers Mass Spectrom. (Tokyo) 5(2),S0053(2016).
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