| Identification | Back Directory | [Name]
CHOLANIC ACID | [CAS]
25312-65-6 | [Synonyms]
CHOLANIC ACID
Einecs 246-816-2 | [EINECS(EC#)]
246-816-2 | [Molecular Formula]
C24H40O2 | [MDL Number]
MFCD00021166 | [MOL File]
25312-65-6.mol | [Molecular Weight]
360.57 |
| Chemical Properties | Back Directory | [Melting point ]
163-164°; mp 163.5° | [alpha ]
D20 +21.7° (chloroform) | [Boiling point ]
432.57°C (rough estimate) | [density ]
1.0086 (rough estimate) | [refractive index ]
1.4480 (estimate) | [pka]
4.76±0.10(Predicted) |
| Hazard Information | Back Directory | [Definition]
ChEBI: A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24. | [Purification Methods]
Crystallise 5-cholanic acid from EtOH, Me2CO or AcOH. The ethyl ester has m 93-94o (from 80% EtOH), b 273o/12mm, [] D 20 +21o (CHCl3), and the methyl ester has m 86-87o (from MeOH) after purification through Al2O3 and eluting with *C6H6, and [] D 20 +21.2o (CHCl3). The 1H NMR (CDCl3) for the C18 & C19 protons has at 0.65 and 0.92ppm [see 5-cholanic acid above, Mandava et al. Steroids 23 357 1974]. [Stoll et al. Helv Chim Acta 18 644 1935, Huang-Minlon J Am Chem Soc 7 1 330 1949, Beilstein 9 III 2656, 9 IV 1992.] |
|
|