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25447-65-8

25447-65-8 Structure

25447-65-8 Structure
IdentificationBack Directory
[Name]

dihydroergocornine
[CAS]

25447-65-8
[Synonyms]

DHO-180
dihydroergocornine
9,10-Dihydroergocornine
Dihydroergocristine Mesylate EP Impurity F
Dihydroergocornine (Dihydroergocristine Mesilate EP Impurity F)
9,10α-Dihydro-12'-hydroxy-2',5'α-diisopropylergotaman-3',6',18-trione
9,10α-Dihydro-12'-hydroxy-2',5'α-bis(isopropyl)ergotaman-3',6',18-trione
9,10α-Dihydro-12'-hydroxy-2',5'α-bis(1-methylethyl)ergotaman-3',6',18-trione
Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2',5'-bis(1-methylethyl)-, (5'α,10α)-
(6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)10b-hydroxy-2,5-bis(1-methylethyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide (dihydroergocornine),
[EINECS(EC#)]

246-992-0
[Molecular Formula]

C31H41N5O5
[MOL File]

25447-65-8.mol
[Molecular Weight]

563.7
Chemical PropertiesBack Directory
[Melting point ]

185-187 °C (decomp)
[Boiling point ]

844.6±65.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[pka]

pKa 6.99±0.02(H2O t=24 I≤0.01) (Uncertain)
Hazard InformationBack Directory
[Uses]

9,10-Dihydroergocornine is used as TAAR receptor agonist for treatment of alopecia.
[Definition]

ChEBI: Ergocornine in which a single bond replaces the double bond between positions 9 and 10.
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