| Identification | Back Directory | [Name]
6-methoxy-8-[[6-methoxy-8-[[6-methoxy-2-methyl-1-(2-methylpropyl)-3,4- dihydro-1H-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihyd ro-1H-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1H -isoquinolin-7-ol | [CAS]
2552-47-8 | [Synonyms]
Pilocereine
1-isobutyl-8-[[1-isobutyl-8-[(1-isobutyl-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)oxy]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
6-methoxy-8-[[6-methoxy-8-[[6-methoxy-2-methyl-1-(2-methylpropyl)-3,4- dihydro-1H-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihyd ro-1H-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1H -isoquinolin-7-ol
7-Isoquinolinol, 1,2,3,4-tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)-8-[[1,2,3,4-tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)-8-[[1,2,3,4-tetrahydro-6-methoxy-2-methyl-1-(2-methylpropyl)-7-isoquinolinyl]oxy]-7-isoquinolinyl]oxy]- | [Molecular Formula]
C45H65N3O6 | [MDL Number]
MFCD00197584 | [MOL File]
2552-47-8.mol | [Molecular Weight]
744.01 |
| Hazard Information | Back Directory | [Description]
A constituent of the cactus Lophocereus Schottii, this alkaloid yields colourless
crystals from AcOEt. The structure is that of a trimeric isoquinoline. A dihydro_x0002_chloride is obtained as the dihydrate, m.p. 228- 232°C (dec.); the diperchlorate
has m.p. 214-7°C; the oxalate forms a crystalline dihydrate, m.p. 158-163°C
(dec.) on rapid heating and m.p. 198- 200°C (dec.) on slow heating. The O-acetate
has m.p. 186°C and the methyl ether exists in two forms as crystals from AcOEt,
m.p. 133-5°C and crystals from hexane which melt at 92-105°C and again at
I 53-5°C after intermediate solidification. The structure has been determined by
chemical degradation and spectroscopic analysis. | [Definition]
ChEBI: Pilocereine is an aromatic ether. | [References]
Djerassi, Frick, Geller., J. Amer. Chern. Soc., 75,3632 (1953)
Djerassi et aI., ibid, 79, 2203 (1957)
Djerassi et al., ibid, 84, 3210 (1962)
Bobbitt, Eberman, Schubert., Tetrahedron Lett., 575 (1963)
Franck, Blasche., ibid, 569 (1963)
|
|
|