| Identification | Back Directory | [Name]
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(2R)-3-[(1S)-1-hydroxy-2-[3-(trifluoromethyl)phenoxy]ethyl]-2-oxiranyl]cyclopentyl]-, 1-methylethyl ester, (5Z)- | [CAS]
2557327-99-6 | [Synonyms]
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(2R)-3-[(1S)-1-hydroxy-2-[3-(trifluoromethyl)phenoxy]ethyl]-2-oxiranyl]cyclopentyl]-, 1-methylethyl ester, (5Z)- | [Molecular Formula]
C26H35F3O7 | [MOL File]
2557327-99-6.mol | [Molecular Weight]
516.55 |
| Hazard Information | Back Directory | [Description]
Fluprostenol isopropyl ester is a potent F-series prostaglandin receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma.1,2 13,14-epoxy Fluprostenol isopropyl ester is an impurity generated in the production of fluprostenol isopropyl ester. This product is a 4:96 diastereomeric mixture of epoxides. | [References]
1. Sorbera, L.A., and Casta?er, J. Travoprost Drugs Future 25(1),41-45(2000).
2. Hellberg, M.R., Sallee, V.L., McLaughlin, M.A., et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist J. Ocul. Pharmacol. Ther. 17(5),421-432(2001). |
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TOSUN PHARM
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www.toref.cn/ |
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