| Identification | Back Directory | [Name]
3'-O-MOE-G(iBu)-2'-phosphoramidite | [CAS]
256224-06-3 | [Synonyms]
3’-O-MOE-G(iBu)-2’-phosphor
3'-O-MOE-G(iBu)-2'-phosphoramidite
5’-O-DMTr-N2-iso-butyroyl-3’-O-(2-methoxy ethyl)guanosine-2’-CED-phosphoramidite
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) | [Molecular Formula]
C47H60N7O10P | [MDL Number]
MFCD31814039 | [MOL File]
256224-06-3.mol | [Molecular Weight]
914.01 |
| Chemical Properties | Back Directory | [pka]
9.16±0.20(Predicted) | [InChIKey]
BWLKVJLYUDLOLH-KEFUZROQNA-N | [SMILES]
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=NC3C(NC(NC(=O)C(C)C)=NC2=3)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]1OCCOC |&1:25,27,44,59,r| |
| Hazard Information | Back Directory | [Description]
3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)
| [Chemical Properties]
White to off-white powder
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