| Identification | Back Directory | [Name]
Madurensine | [CAS]
26126-78-3 | [Synonyms]
Madurensine
4H-1,13-Methano[1,7]dioxacyclotridecino[4,3-b]pyrrole-6,11-dione, 10-ethylidene-2,7,8,9,10,13,14,14a-octahydro-7,14-dihydroxy-7,8-dimethyl-, (7R,8R,10E,13S,14R,14aR)- | [Molecular Formula]
C18H25NO6 | [MOL File]
26126-78-3.mol | [Molecular Weight]
351.39 |
| Hazard Information | Back Directory | [Description]
A hepatotoxic alkaloid first obtained from Crotalaria madurensis and given the
formula ClsH2S06N, revised to that given above by Crout. The base has also
been obtained from the seeds of C. laburnifolia var. eldomae indigenous to
Kenya and Tanzania. It forms short, colourless needles from Me2CO and on acid
hydrolysis furnishes crotanecine and integerrinecic acid. | [References]
Atal et al., Tetrahedron Lett., 537 (1966)
Revised structure:
Culvenor, Smith, Willing., Chem. Commun., 65 (1970)
Revised formula and structure:
Crout., J. Chem. Soc., Perkin I, 1602 (1972) |
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