| Chemical Properties | Back Directory | [Boiling point ]
967.6±75.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
13.13±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
SGC3027 is a prodrug form of the protein arginine methyltransferase 7 (PRMT7) inhibitor SGC8158. It is converted by intracellular reductases to SGC8158, which inhibits PRMT7 with an IC50 value of less than 2.5 nM for inhibition of histone H2B (23-37) methylation. SGC3027 inhibits methylation of heat shock protein 70 (Hsp70) in vitro (IC50 = 2.4 μM). See the Structural Genomics Consortium (SGC) website for more information. | [storage]
Store at -20°C |
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