| Identification | Back Directory | [Name]
L-Alanine, N-[2,6-dichloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3,5-dihydroxybenzoyl)amino]- | [CAS]
264275-77-6 | [Synonyms]
XVA143
L-Alanine, N-[2,6-dichloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(3,5-dihydroxybenzoyl)amino]- | [Molecular Formula]
C25H21Cl2N3O8 | [MOL File]
264275-77-6.mol | [Molecular Weight]
562.36 |
| Hazard Information | Back Directory | [Description]
XVA143 is a α/β I allosteric inhibitor of the integrin leucocyte function-associated antigen-1 (αLβ2, LFA-1) which plays crucial roles in T cell adhesion, migration and immunological synapse (IS) formation. Consequently, αLβ2 is an important therapeutic target in autoimmunity. |
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