| Identification | Back Directory | [Name]
5,8,11,14-Eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2,3-dihydroxypropyl ester, (5Z,8Z,11Z,14Z)- | [CAS]
2692624-29-4 | [Synonyms]
5,8,11,14-Eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2,3-dihydroxypropyl ester, (5Z,8Z,11Z,14Z)- | [Molecular Formula]
C23H38O4 | [MOL File]
2692624-29-4.mol | [Molecular Weight]
378.55 |
| Hazard Information | Back Directory | [Description]
1-Arachidonoyl-d8-rac-glycerol (1-AG-d8) is intended for use as an internal standard for the quantification of 1-AG by GC- or LC-MS. 1-AG is a weak cannabinoid (CB1) receptor agonist and may have other pharmacologic properties.1 1-AG is an isomer of 2-AG. 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. | [References]
1. Sugiura, T., Kodaka, T., Kondo, S., et al. Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells J. Biochem. 122(4),890-895(1997). |
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