ChemicalBook--->CAS DataBase List--->270249-38-2

270249-38-2

270249-38-2 Structure

270249-38-2 Structure
IdentificationBack Directory
[Name]

2'-O-Methylkurarinone
[CAS]

270249-38-2
[Synonyms]

2'-O-Methylkurarinone
Kurarinone, 2'-O-methyl-
(2S)-2-Methoxykurarinone
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)-
[Molecular Formula]

C27H32O6
[MDL Number]

MFCD21333216
[MOL File]

270249-38-2.mol
[Molecular Weight]

452.54
Chemical PropertiesBack Directory
[Melting point ]

112-115℃
[Boiling point ]

643.6±55.0 °C(Predicted)
[density ]

1.171±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

7.50±0.40(Predicted)
[color ]

Light yellow to brown
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

2''-Methoxykurarinone can be used to determine the cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells.
[Definition]

ChEBI: (2S)-2'-methoxykurarinone is a dimethoxyflavanone that is (2S)-(-)-kurarinone in which the hydroxy group at position 2' is replaced by a methoxy group. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a dimethoxyflavanone, a dihydroxyflavanone and a member of 4'-hydroxyflavanones. It is functionally related to a (2S)-(-)-kurarinone.
[storage]

4°C, protect from light
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