| Hazard Information | Back Directory | [Description]
AM2201 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of AM2201 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. AM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively.1 AM2201 N-(4-hydroxypentyl) metabolite is an expected urinary metabolite of AM2201, based on the known metabolism of similar compounds.2 Its biological actions are unknown. | [References]
1. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives US7241799B2,(2001).
2. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010). |
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