| Identification | Back Directory | [Name]
N-Boc-N-bis(PEG1-OH) | [CAS]
275385-03-0 | [Synonyms]
N-Boc-N-bis(PEG1-OH)
N-Boc-N-bis(PEG2-OH)
Carbamic acid, N,N-bis[2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C13H27NO6 | [MDL Number]
MFCD30723207 | [MOL File]
275385-03-0.mol | [Molecular Weight]
293.36 |
| Chemical Properties | Back Directory | [Boiling point ]
419.1±40.0 °C(Predicted) | [density ]
1.121±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [pka]
14.08±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
N-Boc-N-bis(PEG1-OH) is a small PEG linker compound with two terminal hydroxy groups and a Boc protected amino group. The hydroxy groups enable further derivatization or replacement with other reactive functional groups. Boc can be deprotected under acidic conditions. | [Biological Activity]
N-Boc-N-bis(PEG1-OH) is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). | [in vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | [target]
| Cleavable | PEGs | Alkyl/ether | |
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