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27570-20-3

27570-20-3 Structure

27570-20-3 Structure
IdentificationBack Directory
[Name]

Betulin-3-acetate
[CAS]

27570-20-3
[Synonyms]

3-Acetyl Betulin
Betulin-3-acetate
Betulin monoacetate
3β-Acetoxylupa-20(29)-ene-28-ol
Lup-20(29)-ene-3β,28-diol 3-acetate
Lupane-20(29)-ene-3β,28-diol 3-acetate
Betulin 3-O-acetate, 97%, Semi-Synthetic
Lup-20(29)-ene-3,28-diol, 3-acetate, (3β)-
[Molecular Formula]

C32H52O3
[MOL File]

27570-20-3.mol
[Molecular Weight]

484.75
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMF: 5 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Biological Activity]

3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity.
[storage]

-20°C
[References]

1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007) 2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)
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