| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- | [CAS]
2763260-30-4 | [Synonyms]
3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- | [Molecular Formula]
C14H9F3N6O2 | [MOL File]
2763260-30-4.mol | [Molecular Weight]
350.26 |
| Chemical Properties | Back Directory | [density ]
1.617±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 83.33 mg/mL (237.91 mM; Need ultrasonic) | [form ]
Solid | [pka]
4.17±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
NRX-1933 is a β-catenin:β-TrCP interaction enhancer for the development of small molecule degraders. | [References]
[1]. Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402. |
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DC Chemicals
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