| Identification | Back Directory | [Name]
(S)-N-Fmoc-2-(2'-propylenyl)alanine | [CAS]
288617-71-0 | [Synonyms]
FMoc-α-Me-Gly(Allyl)-OH
Fmoc-alpha-All-D-Ala-OH
(S)-N-Fmoc-A-Allylalanine
(S)-N-FMOC-Α-ALLYLALANINE
(S)-N-Fmoc-alpha-allylalanine
Fmoc-(S)-2-(2-propenyl)Ala-OH
Fmoc-(S)-2-(2-propenyl)alanine
Fmoc-alpha-methyl-L-allylglycine
(S)-N-Fmoc-α-2-n-propenylalanine
(S)-N-Fmoc-2-(2'-propenyl)alanine
(S)-N-Fmoc-2-(2'-propylenyl)alanine
(2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid
N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine
(S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine
(9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH
(2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid
4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)- | [Molecular Formula]
C21H21NO4 | [MDL Number]
MFCD02682444 | [MOL File]
288617-71-0.mol | [Molecular Weight]
351.4 |
| Chemical Properties | Back Directory | [Boiling point ]
564.3±45.0 °C(Predicted) | [density ]
1.224 | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
liquid | [pka]
3.81±0.11(Predicted) | [color ]
pale yellow | [InChIKey]
FNCSRFHDUZYOCR-NRFANRHFSA-N |
| Hazard Information | Back Directory | [Uses]
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake. |
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