ChemicalBook--->CAS DataBase List--->292615-75-9

292615-75-9

292615-75-9 Structure

292615-75-9 Structure
IdentificationBack Directory
[Name]

CAY10506
[CAS]

292615-75-9
[Synonyms]

CAY10506
CAY10506 Exclusive
1,2-Dithiolane-3-pentanamide, N-[2-[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-
N-[2-[4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenoxy]ethyl]-5-(dithiolan-3-yl)pentanamide
[Molecular Formula]

C20H26N2O4S3
[MDL Number]

MFCD18427945
[MOL File]

292615-75-9.mol
[Molecular Weight]

454.62
Chemical PropertiesBack Directory
[Boiling point ]

722.0±40.0 °C(Predicted)
[density ]

1.305±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 5 mg/ml; DMSO: 5 mg/ml; DMSO:PBS(pH 7.2) (1:5): 0.15 mg/ml; Ethanol: 3 mg/ml
[pka]

6.35±0.50(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H302-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P312-P330-P303+P361+P353-P304+P340-P305+P351+P338-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

Anti-diabetic drugs of the thiazolidinedione (TZD) structural class as well as α-lipoic acid activate peroxisome proliferator-activated receptor γ (PPARγ), a nuclear transcription factor that controls glucose metabolism and lipid homeostasis. CAY10506 is a hybrid lipoic acid-TZD derivative that transactivates human PPARγ with an EC50 value of 10 μM.
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