Chemical Properties | Back Directory | [density ]
1.350±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid | [pka]
13.71±0.20(predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Biological Activity]
Cell permeable high affinity ligand of RNA-binding protein NONO; stabilize NONO–RNA interactions and rapidly reduces the expression of transcripts encoding AR and AR variants.
(R)-SKBG-1 is a cell permeable high affinity ligand of RNA-binding protein NONO th at binds to Cys 145 of NONO and stabilize NONO–RNA interactions. (R)-SKBG-1 rapidly and stereoselectively reduces the expression of transcripts encoding the androgen receptor (AR) and its splice variants in prostate cancer cells. |
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Company Name: |
cjbscvictory
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Tel: |
13348960310 13348960310 |
Website: |
https://www.weikeqi-biotech.com/ |
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