| Identification | Back Directory | [Name]
Bay 41-4109 | [CAS]
298708-81-3 | [Synonyms]
Bay 41-4109
Bayer 41-4109
BAY41-4109; BAY-41-4109; BAYER 41-4109
methyl (R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate
5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)- | [Molecular Formula]
C18H13ClF3N3O2 | [MOL File]
298708-81-3.mol | [Molecular Weight]
395.76 |
| Chemical Properties | Back Directory | [Boiling point ]
475.3±45.0 °C(Predicted) | [density ]
1.46±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (252.68 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
5.43±0.60(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with IC50 value of 53 nM. | [in vivo]
BAY 41-4109 reduces viral DNA in the liver and in the plasma dose-dependently with efficacy comparable to 3TC. BAY 41 -4109 reduces hepatitis B virus core antigen (HBcAg) in livers of HBV-transgenic mice. | [target]
| [storage]
Store at -20°C |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
|