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30195-30-3

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30195-30-3 Structure

30195-30-3 Structure
IdentificationBack Directory
[Name]

Ro 5-3335
[CAS]

30195-30-3
[Synonyms]

Ro 5-3335
NSC-66020
CBFβ-Runx1 inhibitor II
CBFβ-Runx1 inhibitor II
7-Chloro-5-(1H-pyrrol-2-yl)-1H-benzo[e][1,4]diazepin-2(3H)-one
7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
7-Chloro-2-oxo-5-(1H-pyrrol-2-yl)-2,3-dihydro-1H-1,4-benzodiazepine
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-
Ro5-3335,Ro53335,CBFβ,inhibit,binding,Ro-5-3335,core,RUNX1,RUNX1-CBFB,factor,CBF,interaction,leukemia,Inhibitor,Ro5 3335
[Molecular Formula]

C13H10ClN3O
[MDL Number]

MFCD00870704
[MOL File]

30195-30-3.mol
[Molecular Weight]

259.69
Chemical PropertiesBack Directory
[Melting point ]

256 °C(dec.)
[solubility ]

Soluble to 100 mM in DMSO
[form ]

powder to crystal
[color ]

White to Light red to Green
Safety DataBack Directory
[HS Code ]

2933.99.8290
Hazard InformationBack Directory
[Uses]

Ro 5-3335 is a benzodiazepine is a core binding factor (CBF) leukemia inhibitor.
[Definition]

ChEBI: A 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivati n.
[storage]

Store at +4°C
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